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Author

A. Ratan

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Open access Sep 2026

Biallelic DAW1 variants reveal a tissue-specific role in heterotaxy without primary ciliary dyskinesia

Functional criteria for interpreting DAW1 variants is established, how developmental context clarifies genotype–phenotype relationships is shown, and how in vivo models can support ACMG reclassification of unresolved HTX-related variants are highlighted.

Dana Urbatsch, Anburaj Jeyaraj, Shruti Bedekar et al. · 1 citation
Review Open access Aug 2026

G-quadruplex structures as regulators of cellular processes and drivers of genome instability in cancer.

Therapeutically targeting G4s requires balancing their essential regulatory roles with their pathological effects, and understanding this tension is essential for exploiting G4s as therapeutic targets across cancer types.

Anna R. Bartosik, Magda Bujnowska, D. B. Stovall et al. · 0 citations

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