Change in gut microbiome precedes symptomatic Alzheimer's disease and is correlated with amyloid-beta accumulation in the brain
INTRODUCTION: Alzheimer's disease (AD) begins with cerebral amyloid-beta (A{beta}) deposition decades before clinical symptoms. While the microbiota-gut-brain axis has been implicated in AD, its role in this preclinical phase remains unclear. We examined potential links between gut microbiome features and presymptomati...