Open access
Sep 2026
Genetic and epigenetic architecture of mass spectrometry-derived lipids in blood and their role in lifetime Major Depressive Disorder
The integration analysis showed that genetic variants and DNA methylation at sites annotated to the FADS gene cluster were linked with lipid species that were also associated with lifetime MDD status, while introducing DNA methylation as an additional molecular layer supporting this link.
H. Smith, A. Richmond, M. Adams et al.
· medRxiv · 0 citations