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Review Open access Sep 2026

Interferon crosstalk at the lung barrier in viral and fungal infection

ABSTRACT Interferons (IFNs) coordinate host defense at the lung barrier by linking pathogen recognition to epithelial and immune-cell responses. Their effects are highly context-dependent and can be protective or pathological according to IFN class and ligand, cellular source and target, and the timing and duration of...

Maria Velez-Brochero, A. Rivera · 0 citations
Jul 2026

Dissecting the Role of Type I Interferon as Regulator of Innate Antifungal Immunity 2227148

Aspergillus fumigatus (Af) is the main cause of invasive pulmonary aspergillosis (IA), responsible for over 90% of cases, and has been identified by the World Health Organization (WHO) as the only mold among its list of critical fungal pathogens.Myeloid cells, CCR2+ inflammatory monocytes (CCR2+Mo), and neutrophi...

Angelica Gonzalez-Martinez, V. Espinosa, A. Rivera · 0 citations

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