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Author

A. Robaszkiewicz

2 papers indexed here

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Open access Aug 2026

Txn-Txnrd1 system supports redox rewiring during polyaneuploid transition and protects giant cancer cells at new redox homeostasis

Polyaneuploid giant cells (PGCC), which occur more frequently in TP53-mutant tumors, are recognized as a driver of tumor recurrence and therapy resistance, but the mechanisms supporting their survival remain largely unknown. Our results indicate that polyaneuploid transition and subsequent PGCC maturation in drug-resis...

Kinga Kołacz-Milewska, K. Gronkowska, Sylwia Michlewska et al. · 0 citations
Open access Aug 2026

Lipid anchor engineering controls cell-penetrating arginine-rich peptide presentation for efficient siEGFR liposomal delivery to triple-negative breast cancer cells

Understanding the physicochemical factors that govern siRNA nanocarrier assembly is essential for the rational design of effective delivery systems. By optimizing various lipid compositions, cholesterol content and PEG length we created a peptide-functionalized cationic liposomal platform made of DOPE/TAP lipids with c...

P. Białecki, S. Braccia, T. Makowski et al. · 0 citations

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