Review
Open access
Sep 2026
Interkingdom microbiome physiology in colorectal cancer: barrier dysfunction, immune-metabolic signaling, and therapeutic resistance
Colorectal cancer develops within a physiologically altered intestinal ecosystem. Epithelial barrier disruption, chronic inflammatory signaling, immune remodeling, and metabolic rewiring reshape host-microbial interactions in this niche. Although most colorectal cancer microbiome reviews have emphasized bacterial taxa,...
Shamim Pourbahrighesmat, Alireza Tojjari, G. Laliotis et al.
· Frontiers in Physiology · 0 citations