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Author

A. Safar

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2 papers indexed here

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Sep 2026

The aryl hydrocarbon signaling pathway in the ovary changes throughout reproductive aging and in response to a mixture of phthalates over time in mice.

Phthalates are plasticizers and solvents used in numerous consumer products. Exposure to a phthalate mixture (Mix) alters estrous cyclicity, fertility indices, ovarian follicle dynamics, and steroidogenesis. In cultured antral follicles, phthalates alter the aryl hydrocarbon receptor (AHR) pathway, which is known for e...

A. E. Dean, R. Santacruz-Márquez, A. Safar et al. · 0 citations
Sep 2026

Exposure to di(2-ethylhexyl) phthalate and diisononyl phthalate alters the aryl hydrocarbon receptor signaling pathway in the ovary throughout reproductive aging in mice.

Di(2-ethylhexyl) phthalate (DEHP) and diisononyl phthalate (DiNP) are plasticizers used in many consumer products. Both phthalates alter estrous cyclicity, fertility indices, and folliculogenesis throughout the reproductive lifespan. Our companion paper showed that exposure to a phthalate mixture containing DEHP and Di...

A. E. Dean, R. Santacruz-Márquez, A. Safar et al. · 0 citations

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