Efficacy and safety of biologic therapies for chronic rhinosinusitis with nasal polyps: a systematic review and meta-analysis
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous, type 2-inflammation-driven disease of the sinonasal mucosa that is frequently refractory to intranasal and systemic corticosteroids and often recurs after endoscopic sinus surgery. Biologic agents targeting distinct upstream and downstream type 2 inf...