Author

A. Samaddar

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Open access Aug 2026

Age-stratified mutation patterns in early-onset colorectal cancer reveal distinct molecular features and therapeutic implications

Differences in mutations of key genes including a lower prevalence of APC mutations and increased SMAD4 mutations in younger individuals provides further supporting evidence that early-onset CRC may represent a distinct biological subtype of CRC.

L. Liu, A. Rose, A. Samaddar et al. · ESMO gastrointestinal oncolo... · 0 citations