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Author

A. Sandoval-Rodríguez

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2 papers indexed here

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Open access Sep 2026

Adenoviral-Mediated SIRT1 Expression Restores Lung Architecture and Reduces Fibrotic Progression in Experimental Models.

Background: Pulmonary fibrosis (PF) involves remodeling of lung architecture and limited therapeutic options are available. Sirtuin 1 (SIRT1), an epigenetic regulator, has emerged as a promising antifibrotic target due to its role in apoptosis, inflammation, and chromatin remodeling. Methods: We evaluated the effects o...

Liliana Faridi Saavedra-Salazar, Nayabei Ruiz Ramirez, Hugo Christian Monroy-Rami Rez et al. · 0 citations
Open access Aug 2026

Pirfenidone restores metabolic hormones and cardiac autophagy via p-AMPK in MASH

Obesity promotes chronic inflammation and insulin resistance, disrupting key metabolic hormones (e.g., insulin and leptin) and triggering metabolic dysfunction-associated steatohepatitis (MASH). Obesity is commonly associated with cardiovascular disease. Autophagy preserves heart function in response to various stresse...

D. López-Cifuentes, A. Sandoval-Rodríguez, Rebeca Escutia-Gutiérrez et al. · 0 citations

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