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A. Scalco

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Open access Oct 2026

Macrophage-derived HB-EGF activates EGFR signaling to impair atherogenic macrophage–vascular smooth muscle cell crosstalk in ASCVD

Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of death worldwide. Despite advances in lipid-lowering therapies, substantial residual cardiovascular risk persists, highlighting the need to identify non-lipid-mediated mechanisms of disease susceptibility. Inflammation plays a central role...

A. Scalco, E. Ziogos, P. Toledano-Sanz et al. · 0 citations

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