HA suppressed pro-inflammatory cytokines while up-regulating IL-10 in IL-1β-exposed gMSCs, restoring cell viability and accelerating wound closure under inflammatory conditions, which support the rationale for HA's clinical use in periodontal therapy.
S. Hakki, Darko Božić, A. Sculean et al.· Journal of Clinical Periodon...· 0 citations
The history of EV research reflects a remarkable transition from observations of poorly understood extracellular particles to the recognition of EVs as key modulators of biological communication and potential therapeutic systems.
R. Miron, Paras Ahmad, A. Sculean· Periodontology 2000· 1 citation
Current regenerative approaches lead to long‐term stable outcomes at natural teeth as well as dental implant sites; novel technologies can benefit patients by enhancing longer‐term stability of teeth and implants to promote the health of the oral cavity and dentition.
Mariano Sanz, S. Ivanovski, J. Nart et al.· The Journal of Periodontolog...· 0 citations
Dental implants are highly durable in terms of retention, but high survival does not establish long-term biological health or true treatment success: success rates were lower and definition-dependent, and peri-implant disease showed substantial variability.
V. Moraschini, Krisztina Mikulás, J. A. Shibli et al.· Periodontology 2000· 0 citations
OBJECTIVE
Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction-associated steatotic liver disease (MASLD) and its progressive phenotypes, have eme...
R. S. de Molon, E. D. de Avila, D. da Silva Barbirato et al.· Periodontology 2000· 1 citation
BACKGROUND AND AIM
To investigate the effect of periodontal treatment on periodontal inflammation and periostin levels in patients with severe periodontitis.
METHODS
This study included two groups (periodontitis and periodontally healthy), each comprising 24 individuals. Periodontal clinical parameters were recorded,...
Aysegul Sarı, O. Ozcan, F. Kaçmaz et al.· Journal of Clinical Periodon...· 0 citations
EVs represent promising therapeutic agents and biomarkers in aging biology, with the potential to regulate multiple hallmarks of aging concurrently, and should be prioritized for successful antiaging interventions.
Paras Ahmad, N. Estrin, A. Sculean et al.· Periodontology 2000· 0 citations
AIM
This systematic review and meta-analysis aimed to compare soft and hard tissue outcomes of applying anatomic healing abutments (AHA) and provisional restorations (PR) versus cylindrical healing abutments (CHA) on immediately placed single implants.
MATERIALS AND METHODS
Four databases (PubMed, Embase, Cochrane, a...
Xinyi Qian, Boldizsár Vánkos, G. Agócs et al.· Periodontology 2000· 0 citations
The multifunctional coating provides sustained antimicrobial activity alongside immunomodulatory and pro-regenerative effects, supporting its potential to treat implant-related infections while enhancing peri-implant soft tissue remodeling.
Mariana Martins Guerreiro, Amanda Paino Santana, D. M. Cunha et al.· Journal of Periodontal Resea...· 0 citations
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