Open access
Aug 2026
CHEK2 Germline Variants in Cancer Predisposition: Whole Genome Sequencing Results
While pathogenic germline CHEK2 variants are known to increase cancer risk, there is currently insufficient evidence regarding the precise risk of developing malignant neoplasms associated with specific missense variants or variants of uncertain significance. As a result, no clear clinical guidelines exist regarding co...
M. Nemtsova, M. Makarova, Anastasiia M. Danishevich et al.
· International Journal of Mol... · 0 citations