Some of the advantages of familial data using the Norwegian Mother, Father and Child Cohort Study (MoBa), a population-based cohort of parents and offspring with extensive genotype data, are illustrated along with broad and longitudinal phenotyping of health and functioning.
E. Corfield, A. Shadrin, O. Frei et al.· Nature· 3 citations
Compared to males, female patients with DLB were less likely to present with Rapid Eye Movement (REM) Sleep Behaviour Disorder, CSF biomarkers showed more Alzheimer’s Disease (AD) co-pathology, potentially contributing to misdiagnosis of DLB.
Heidi Isaksen, K. F. Bru, A. Shadrin et al.· npj Dementia· 0 citations
By dissecting the genetic liability to SUD and SU and investigating their relationship with BIP, this work finds a genetic signature correlated with substance dependence but not substance use more broadly.
L. Ystaas, P. Parekh, N. Parker et al.· Biological Psychiatry· 0 citations
Bipolar disorder’s genetic architecture appears hierarchical—a general liability resolving into dimensions of course and comorbidity, beyond subtypes, beyond subtypes.
Tracey van der Veen, M. Tesfaye, J. M. K. Yang et al.· Research Square· 0 citations
It is found that schizophrenia and ADHD show distinct genetic patterns: schizophrenia shares more genetic factors with brain structure and diabetes, while ADHD is more strongly linked to metabolic pathways.
J. Kopal, A. Shadrin, D. van der Meer et al.· Communications Medicine· 0 citations
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