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Author

A. Shilatifard

2 papers indexed here

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Open access Sep 2026

POU2AF2/OCA-T1 coactivates POU2F2 and defines a lineage-specific dependency in diffuse large B-cell lymphoma

Lineage-restricted transcriptional programs establish cell identity and can create selective dependencies in cancer. Here, we identify POU2AF2, encoding the transcriptional co-activator OCA-T1, as a critical lineage-specific dependency in a subset of diffuse large B-cell lymphoma (DLBCL). Pan-cancer dependency analyses...

Rima Tulaiha, Liam Shanley, Amanda Luvisotto et al. · 0 citations
Review Aug 2026

Transcriptional kinases drive gene expression network plasticity.

Eukaryotic transcription is a highly dynamic and adaptable process that underpins the gene expression programs regulating development, cellular identity, and responses to extracellular signals. Gene-specific regulation of transcription across different cell types and environmental conditions is therefore fundamental to...

David D. Lowe, A. Shilatifard · 0 citations

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