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Open access Sep 2026

Structure based discovery of VMP-7 as a promising GlgE targeting lead against Mycobacterium tuberculosis

Tuberculosis (TB), caused by Mycobacterium tuberculosis (M.tb), remains a major global health challenge, necessitating the identification of novel drug targets with high specificity and therapeutic potential. Maltosyltransferase (GlgE) is a critical enzyme in the biosynthesis of cytosolic α-glucan, a key component requ...

Pratik Mahajan, Sushama Jadhav, A. Singh et al. · 0 citations
Open access Aug 2026

L-Serine potentiates the efficacy of Isoniazid, and Rifampicin as host-directed adjunctive treatment for Mycobacterium tuberculosis

L-Serine is an important metabolic and immunomodulatory biomolecule with promising role in managing infections, and autoimmune diseases. L-Serine provides the energy requirements and triggers the toll-like receptor signalling collaterally. However, the role of L-Serine in host antimicrobial response against Mycobacteri...

Niharika Sharma, Rahul Sharma, Abhishek Kumar et al. · 0 citations

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