A. Sniderman

Interplay of HDL cholesterol and apoB and the risk of incident atherosclerotic cardiovascular disease in UK Biobank.

BACKGROUND Apolipoprotein B (apoB) is the most accurate causal lipid factor associated with increased risk of atherosclerotic cardiovascular disease (ASCVD). While high HDL cholesterol has been considered protective, HDL-C-raising therapies have not shown benefit. OBJECTIVE To assess whether HDL-C provides independen...