Author

Â. Sousa

2 papers indexed here

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Open access Oct 2026

Integrated Two-Step Membrane Chromatography for Robust and High-Throughput Plasmid DNA Purification

Plasmid DNA (pDNA) is a key raw material for advanced therapeutic modalities, including gene therapy, mRNA production, and DNA vaccination, requiring efficient and scalable downstream processing strategies. Increasing demand places stringent requirements on purification processes in terms of yield, impurity removal, pr...

Matilde Costa, S. Cardoso, I. Marçal et al. · Membranes · 0 citations

Open access Jul 2026

Peptide-Based Nanocomplexes Enable Transferrin-Mediated Uptake and p53-Driven Antitumor Activity in 2D and 3D Glioblastoma Models

The potential of this targeted and tailored nanosystem to enhance cellular transfection, enable drug/gene co-delivery, restore p53 function, and promote apoptosis is highlighted, representing a promising therapeutic strategy for GB treatment.

Leonor M. Castro, A. Neves, Eric Vivès et al. · International Journal of Mol... · 0 citations