Open access
Aug 2026
Multifunctional nanoparticles for co-delivery of elacridar and paclitaxel for breast cancer local treatment.
In an in vivo model of breast cancer, intraductal H-NPs reduced tumor incidence and volume compared to a drug solution, and increased the mammary tissue-to-plasma ratio of paclitaxel by 105-fold, supporting an improved tissue retention, support H-NPs as promising platforms for localized breast cancer therapy.
J. S. Passos, G. C. Salata, G. B. de Melo et al.
· International journal of pha... · 0 citations