A. Suri

Plasma Cell-Free DNA-Based Next-Generation Sequencing for Molecular Profiling of Diffuse Gliomas

To evaluate the utility of plasma-derived cell-free DNA (cfDNA) using targeted next-generation sequencing (NGS) for molecular profiling of diffuse gliomas (DG) by assessing concordance with matched tumor tissue DNA, mutation profiles, variant allele frequencies, therapeutically actionable alterations, and surviva...

Erdheim–Chester disease: a diagnostic dilemma – a report of four cases

79 Diagnostic Utility of DNA Methylation Profiling in CNS Tumors: A Comparative Study of FFPE and Fresh-Frozen Tissues

DNA methylation–based classification has become an essential adjunct to histopathology in central nervous system (CNS) tumor diagnostics. Although both fresh-frozen and formalin-fixed paraffin-embedded (FFPE) tissues are used for methylation profiling, comparative real-world data on their diagnostic performance r...