Background: Evidence describing the longitudinal effectiveness and tolerability of tirzepatide in adults with obesity and heart failure with preserved ejection fraction (HFpEF) remains limited, particularly from prospective cohorts with repeated cardiometabolic assessments. This study evaluated longitudinal changes in...
A. Tauekelova, Bakhytnur Karipova, A. Zholdybaeva et al.· Journal of Clinical Medicine...· 0 citations
The gut microbiome is known to modulate metabolic health, yet its role in coronary heart disease (CHD) and heart failure with preserved ejection fraction (HFpEF) remains unclear. In the present study, we profiled the gut microbiome of 234 participants using shotgun metagenomic sequencing across controls (n = 43), indiv...
A. Tauekelova, N. Katkenov, S. Kozhakhmetov et al.· Frontiers in Microbiology· 0 citations
This study aimed to evaluate platform-specific immune memory trajectories in patients with breakthrough COVID-19 over a 12-month period. This prospective longitudinal study enrolled adults hospitalized with PCR-confirmed COVID-19. Participants were stratified according to prior COVID-19 vaccination status into three gr...
L. Akhmaltdinova, M. Bekbossynova, Kuanysh Dossybayeva et al.· Microorganisms· 0 citations
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