Mapping the Conformational Landscape of the Cold-Regulated Intrinsically Disordered Protein COR15A.
Cold regulated protein 15A (COR15A) is a late embryogenesis abundant (LEA) protein from Arabidopsis thaliana that is expressed in response to low temperatures and dehydration. Here, we use a combination of ion mobility-mass spectrometry (IM-MS) and molecular dynamics (MD) simulations at elevated temperatures for enhanc...