Regulatory T cells are well known for their immunomodulatory role but also their regenerative function is increasingly recognized across multiple tissue types including skeletal muscle, lung and the central nervous system (CNS). In the CNS, Tregs have been shown to promote oligodendrocyte precursor cell differentiation...
Sarah Chenine, A. Tiane, P. Baeten et al.· Frontiers in Immunology· 0 citations
A myelin‐centered framework for tau pathology based on three mechanisms suggests that myelin loss may contribute to tau accumulation, clearance deficits, and spread, providing a framework for future experimental testing.
A. Tiane, D. V. D. van den Hove, T. Vanmierlo· Alzheimer's & Dementia· 0 citations
This work identified a specific vulnerability of cortical grey matter myelin in AD, whereas white matter myelin appeared relatively preserved, and highlighted the tight intertwining of oligodendrocyte and myelin dynamics with tau-associated neurodegeneration.
A. Tiane, Emily Willems, Lisa Koole et al.· bioRxiv· 0 citations
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