Open access
Oct 2026
Galantamine Ameliorates Doxorubicin-Induced Cognitive Impairment in Female Rats via Modulation of Neuroinflammation, BDNF/TrkB Pathway and Synaptic Plasticity
Background: Chemotherapy-related cognitive impairment is a debilitating neurocognitive syndrome with no approved treatment. Doxorubicin induces neuroinflammation, disrupts neurotrophic signaling, and impairs synaptic plasticity. Galantamine, an acetylcholinesterase inhibitor, has anti-inflammatory and neuroprotective p...
S. Saral, Ayşegül Sümer, A. Topçu et al.
· Pharmaceuticals · 0 citations