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Open access Sep 2026

DCE-MRI and Mammography integrated radiomic analysis in triple negative ductal invasive breast cancer patients. Comparison between BRCA and not BRCA mutated patients: preliminary results

Purpose We propose a combined radiomic model based on features extracted from DCE-MRI and mammographic images (MG) to discriminate the mutational status of BRCA genes in patients with TNBC. Material and methods This retrospective study included patients histologically diagnosed with TNBC who performed a mammography fol...

A. Pecchi, Cecilia Beretta, Erica Balboni et al. · 0 citations
Review Open access Sep 2026

Clinical Implications of the Type and Genomic Location of Pathogenic BRCA1 and BRCA2 Variants in Hereditary Breast and Ovarian Cancer.

Germline pathogenic or likely pathogenic variants (P/LPVs) in BRCA1 and BRCA2 are major determinants of hereditary breast and ovarian cancer susceptibility. Although clinical management has traditionally relied on the presence of a BRCA1/BRCA2 alteration regardless of its specific characteristics, growing evidence sugg...

Emma Zattarin, C. Piombino, E. Tenedini et al. · 0 citations

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