Sep 2026
IDH3 regulates citrate homeostasis to control metabolic fitness and venetoclax resistance of AML stem cells.
Aykut Demir, Maximilian Mönnig, Nesrine Aroua et al.
· Blood · 0 citations
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Aug 2026
Perturb-seq identifies co-regulated gene programs shaping hematopoietic stem and progenitor cell function
Perturbation-derived co-regulation programs are established as an interpretable framework for linking genetic regulators, cell-biological processes and stem-cell-associated phenotypes by decomposing gene expression data from functional and clinical studies into program activity.
Joseph S. Bowness, Aina Bernal Martínez, Jan Bařinka et al.
· bioRxiv · 0 citations