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Open access Oct 2026

In silico identification and design of 2-(3-methoxyphenoxy)-N-methylacetamide analogs as anti-tuberculosis transcriptional regulator (EthR) inhibitors via E-pharmacophore modeling, QSAR, docking, MMGBSA, ADMET, and molecular dynamics

Tuberculosis (TB) remains a leading cause of infectious mortality worldwide, exacerbated by the emergence of multidrug-resistant strains and the dose-limiting toxicity of existing chemotherapeutics. Targeting regulatory mechanisms that potentiate current drugs offers a promising alternative strategy. EthR, a TetR-famil...

Anne Jibrin, A. Uzairu, Imran Mohd et al. · 0 citations
Open access Aug 2026

Lignin-degrading-inspired dehydrogenative photocatalysis via reductive quenching of donor-acceptor covalent organic framework

Achieving a photocatalytic reductive quenching cycle that enables direct oxidation of the photocatalyst radical anion by H(I) species, without requiring stoichiometric oxidants or cocatalysts, remains a long-standing challenge in artificial photoredox catalysis. Here we report a bioinspired approach based on the lignin...

Xiang-Feng Lin, A. Umar, Jia-Xian Zheng et al. · 0 citations

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