Open access
Sep 2026
Single cell RNA-sequencing reveals neuron type-specific vulnerabilities in a model of STXBP1-related disorder.
Cell-type specific vulnerabilities to STXBP1 haploinsufficiency are identified which may explain hyperexcitability, network dysfunction and cognition deficits in STXBP1-RD, providing potential new therapeutic targets.
A. R. Adam, A. V. van Berkel, M. Vanheusden et al.
· Molecular Psychiatry · 0 citations