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A. Vaudano

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Open access Oct 2026

Beyond seizure control: Non-seizure-related outcomes in focal-onset epilepsy treated with adjunctive cenobamate. Third interim results from the BLESS study.

OBJECTIVE Cenobamate is approved for treatment of focal seizures in adults, but evidence on non-seizure outcomes remains limited. This interim statistical analysis of the cenoBamate in aduLts with focal-onsEt SeizureS (BLESS) study evaluated patient- and clinician-reported outcomes for up to 52 weeks of cenobamate trea...

Simona Lattanzi, G. d'Orsi, M. T. Di Claudio et al. · 0 citations
Open access Sep 2026

Statin use and risk of remote seizure after first new onset status epilepticus.

OBJECTIVE Preclinical evidence supports the role of statins as antiepileptogenic agents. In this study, we investigated the risk of remote unprovoked seizures (RS) according to the use of statin therapy in a cohort of first-ever status epilepticus (SE) survivors. METHODS Retrospective analysis was made of adult patie...

Niccolò Orlandi, G. Giovannini, Lisa Taruffi et al. · 0 citations
Open access Aug 2026

Cognitive and Biomarker Signatures of Late-Onset Temporal Lobe Epilepsy

Cognitive and CSF phenotype of LO-TLE with normal CSF AD biomarkers is characterized by distinct cognitive and biological features compared with MCI-AD, suggesting a disease process independent of AD.

Alessia Casarini, Alice Ballerini, Riccardo Maramotti et al. · 0 citations

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