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A. Vega-Letter

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Oct 2026

The secretome of UC-MSC reprogrammed to a glycolytic metabolism promotes Treg generation and naive CD4 T cells stability in PBMC from rheumatoid arthritis patients.

OBJECTIVE Rheumatoid arthritis (RA) is characterized by persistent inflammation and dysregulated T cell responses. Mesenchymal stromal cells (MSCs) have immunomodulatory properties, but their clinical efficacy remains variable. We investigated whether metabolic reprogramming of umbilical cord-derived MSCs (UC-MSCs) tow...

N. Luque-Campos, C. Pradenas, E. Lara-Barba et al. · 0 citations

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