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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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A. Verma

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Review Aug 2026

Pharmacokinetic modeling frameworks for complex antibody-drug conjugates analytes: clinical pharmacology considerations.

Antibody-drug conjugates (ADCs) present unique pharmacokinetic (PK) challenges due to analyte heterogeneity, dynamic drug-to-antibody ratio (DAR) distributions, target-mediated disposition, and systemic release of cytotoxic payloads. Unlike monoclonal antibodies or small molecules alone, ADCs require integrated modelin...

Devendra Kumar, A. Verma, Neerja Trivedi · 0 citations

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