Review
Open access
Sep 2026
Methylglyoxal as a Potential Mediator of Metabolic Memory in Diabetes-Related Complications: From Oxidative Stress to Macromolecular Glycation and Epigenetic Remodeling
The role of MGO in metabolic memory is discussed, focusing on oxidative stress, protein glycation, nucleic acid damage and epigenetic remodeling, and highlights emerging therapeutic strategies targeting dicarbonyl stress to prevent the progression of diabetes-related complications.
Maya A. K. Stelzer, A. W. Khan, J. Kroon et al.
· Antioxidants · 0 citations