A. W. Truman

A conserved NLR activation switch governs global transcriptional control of antibiotic biosynthesis in Streptomyces

Nucleotide-binding and oligomerization domain-like receptors (NLRs) are conserved molecular switches that regulate innate immunity across diverse domains of life. While best known for their roles in immunity, bacterial NLR-related proteins also govern non-immune processes. In Streptomyces, the global transcriptional re...