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Author

A. Waters

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Open access Sep 2026

NaV1.7-dependent peripheral sensitization drives chronic pain in Parkinson’s disease

Pain is among the most prevalent and disabling nonmotor symptoms of Parkinson’s disease (PD), yet its mechanisms remain poorly defined and effective treatments are limited. Safinamide is one of the few drugs reported to improve pain in PD, but the mechanism underlying this effect is unknown. Here, we show that nigrostr...

Tyler S. Nelson, Naomi K. Grabus, Heather N. Allen et al. · 1 citation

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