Open access
Sep 2026
The antiproliferative and pro-apoptotic effects of 3-deoxy-3α-fluoro-chenodeoxycholic acid and 12β-methyl-3,7-dioxo-17-epi-25-homo-18-nor-5β-cholan-25-oic acid on human breast cancer cell lines.
Bile acid derivatives have emerged as promising candidates in cancer therapeutics due to their ability to modulate key cellular signalling pathways, including those involved in apoptosis, cell cycle regulation, and inflammation. Structural modifications of natural bile acids have been shown to enhance their cytotoxicit...
Divyashree Ravishankar, Joseph M. Watts, A. Luxenburger et al.
· Bioorganic & Medicinal Chemi... · 0 citations