Author

A. Wicki

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Open access Sep 2026

The liver niche accelerates, while the lung niche restrains secondary spread of breast cancer.

It is shown that breast cancer metastases differ in their capacity for secondary seeding: the liver fosters metastasis-promoting properties and boosts secondary spread, whereas the lung restricts these processes, favoring local growth.

Magdalena K. Sznurkowska, Francesc Castro-Giner, Irene D'Anna et al. · Cancer Discovery · 0 citations

Open access Jul 2026

A tumor profiling resource for ovarian cancer: insights into chemotherapy-driven heterogeneity and personalized treatment strategy

It is demonstrated that integrated multimodal tumor profiling can inform personalized maintenance treatment decisions and that chemotherapy reshapes tumor cell diversity.

Francis Jacob, R. Wegmann, Joanna Ficek-Pascual et al. · Nature Communications · 0 citations

Open access Aug 2026

The Virtual Tissues foundation model resolves spatial proteomics across scales

VirTues-derived biomarkers predict anti-PD-L1 chemo-immunotherapy response and stratify disease-free survival in an independent cohort, outperforming state-of-the-art biomarkers derived from the same datasets and current clinical stratification schemes.

Johann Wenckstern, Eeshaan Jain, Benedikt von Querfurth et al. · Nature · 4 citations