A. Williamson

Progress toward HIV-1 subtype C vaccines: understanding antiviral immune mechanisms and viral adaptation.

INTRODUCTION HIV-1 subtype C (HIV-1C) accounts for most infections globally, with sub-Saharan Africa bearing a disproportionate burden. Despite decades of research and multiple clinical trials, no effective prophylactic vaccine exists for this or any other HIV subtype - and candidate vaccines for subtype C are less wel...