271. Glymphatic system dysfunction, accelerated brain aging, and inflammation in major psychiatric disorders: a transdiagnostic DTI-ALPS study
Abstract Background Major psychiatric disorders, including Schizophrenia (SZ), Bipolar Disorder (BD), and Major Depressive Disorder (MDD), are increasingly recognized as conditions associated with accelerated biological aging and cognitive decline. The glymphatic system, a glial-dependent perivascular network, mediated...