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A. Yeti̇man

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Open access Sep 2026

Discovery of Novel Peptides as DPP-IV Inhibitors: In Silico Screening, Molecular Dynamics Simulations, and Preliminary In Vitro Evaluation

Type 2 diabetes mellitus (T2DM) is the most common metabolic disorder characterized by impaired insulin secretion, which leads to obesity. The incretin hormone glucagon-like peptide-1 (GLP-1) has a significant role in glucose homeostasis, but its native form in the human body is highly susceptible to proteolytic degr...

Burak Çaliş, F. Zanchi, Beyza Canakcimaksutoglu et al. · 0 citations
Open access Aug 2026

Virtual Screening of Bacteriocins From Lactic Acid Bacteria Against Monkeypox DNA Polymerase: Sakacin P and Mundticin KS Emerge as Promising Candidates

The results indicate that bacteriocins, especially Sakacin P and Mundticin KS, can be considered potential antiviral agents against MPXV by interfering with its DNA replication mechanism.

Melisa Z Karaman, Karan Goel, F. Zanchi et al. · 0 citations

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