The gut microbiome has been linked to cancer in many cross-sectional studies. These studies compared individuals with and without cancer, but they do not establish causation. Prospective cohort studies, with faecal samples collected before a cancer diagnosis, will be instrumental in assessing the role of the gut microb...
E. Vogtmann, Caroline Y. Um, S. Zouiouich et al.· The Lancet Microbe· 0 citations
Cancer remains a leading cause of morbidity and mortality worldwide, and the incidence of new cancer cases is rising. While established lifestyle factors such as smoking, obesity, and diet contribute to cancer risk, the gut microbiome has emerged as a hallmark of cancer. However, the role of the gut microbiome in cance...
E. Oosterhout, R. S. Leijdesdorff, O. Kambur et al.· medRxiv· 0 citations
This study provides the most comprehensive assessment of IBS genetics to date, demonstrating reproducible polygenic inheritance and linking IBS risk to convergent neurogastrointestinal and novel cardiometabolic mechanisms, highlight specific biological pathways and actionable mechanisms and outline translational opport...
Biagio Di Lorenzo, L. Camargo Tavares, Cristian Díaz-Muñoz et al.· Gut· 0 citations
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