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A. Zografos

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Open access Jul 2026

Synthetic Framework Evolution: A Scaffold-Centric Perspective on Iterative Chemical Space Expansion.

ConspectusThe efficient exploration of natural product-like chemical space remains a central challenge in synthetic chemistry and chemical biology. Despite major advances, many synthetic strategies remain organized around individual targets or predefined compound collections, which can limit the continuity and cumulati...

Kalliopi Mazaraki, George Karageorgis, A. Zografos · 0 citations

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