A. Zonderman

Life's Simple 7, depressive symptoms, cognitive performance, and their associations with all-cause mortality among middle-aged urban adults.

Association Between Changes in Perceived Neighborhood and Cognitive Performance Within Healthy Aging in Neighborhoods of Diversity Across the Life Span (HANDLS) Black Adults

Highlights Public health relevance—How does this work relate to a public health issue? This work highlights the importance of examining changes in contextual factors (i.e., perceived neighborhood characteristics) as they relate to cognitive function. Public health significance—Why is this work of significance to public...

The proteomic and metabolomic signature of inherited chromosomally integrated HHV‐6 and its role in all‐cause dementia and mortality risk: The UK Biobank study

Examination of associations of inherited chromosomally integrated human herpesvirus 6 with incident dementia and mortality, characterize proteomic and metabolomic correlates of carrier status, and evaluate whether these biomarkers relate to dementia and mortality risk found iciHHV‐6 was associated with increased dement...

The interplay of air pollution with plasma neurodegenerative markers and metabolome for dementia, Parkinson’s Disease and all-cause mortality risks and transitions: the UK Biobank study

Findings highlight complex relationships linking air pollution, metabolic dysregulation, and neurodegeneration, and support integrative multi-omics approaches to identify pathways relevant to prevention of neurodegenerative diseases and premature mortality.

Investigation of psychosocial stress and DNA methylation in genes related to immune response, metabolism, and calcium signaling among African American and White middle-aged adults.

Novel DNAm genes associated with PD transduce effects through biological pathways related to inflammation and immune response, white adipose tissue browning, and calcium signaling are identified.