668. Serotonin, melatonin, and kynurenines: bridging neurochemical pathways in schizophrenia and beyond
Abstract Background Cognitive deficits and metabolic syndrome are highly prevalent in schizophrenia (SCZ), suggesting shared underlying biological mechanisms. Emerging evidence points to the dysregulation of tryptophan (Trp) metabolism, specifically the balance between the serotonin/melatonin (MLT) and kynurenine (Kyn)...