Author

Aaron Hakim

2 papers indexed here

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Open access Sep 2026

OPA1 controls mitochondrial dysfunction-driven liver fibrosis in MASLD

Progressive hepatic fibrosis is the principal determinant of morbidity and mortality in metabolic dysfunction-associated steatotic liver disease and steatohepatitis (MASLD/MASH). Mitochondrial dysfunction is a hallmark of MASH, and the release of mitochondrial damage-associated molecular patterns (mito-DAMPs) from inju...

Xin-Ting Yu, Pin-Zhu Huang, Arvo Justice et al. · bioRxiv · 0 citations

Open access Sep 2026

Role of IFNL4 Genotype in Hepatic Inflammation and Fibrosis due to Metabolic Dysfunction-Associated Steatotic Liver Disease

Background and Aims: In patients infected with hepatitis C virus, genetic polymorphisms within or near the interferon lambda 4 gene (IFNL4) predict the risk of hepatic inflammation and fibrosis. Several studies have reported that these polymorphisms are also associated with inflammation and fibrosis in patients with fa...

Callie J. Zaborenko, Aaron Hakim, Tae-Hwi Schwantes-An et al. · Research Square · 0 citations