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Author

Aarti Shingan

2 papers indexed here

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Aug 2026

Synthesis, In-Vitro, and In-silico analysis of Repurposed Substituted 2,7-Dimethylimidazo [1,2-a]Pyridine-3-Carboxamide based α-Amylase inhibitors via docking, MMGBSA, dynamics simulation techniques and pharmacokinetic evaluation

In-silico ADME studies indicated favorable pharmacokinetic properties, including high gastrointestinal absorption, low TPSA, BBB permeability, and compliance with Lipinskis rule, while toxicity prediction suggested acceptable safety profiles for the synthesized derivatives, highlighting their potential as promising α-a...

Suraj N. Mali, Prachi Singh, Somdatta Y. Chaudhari et al. · 0 citations
Aug 2026

A highly efficient one-pot approach for the synthesis of novel 5-amino-4-Cyano-Pyrazoles with promising anti-inflammatory and broad-spectrum antimicrobial activity.

A green and efficient one-pot synthetic method has been developed to prepare novel 5-amino-3-(aryl)-1-(aryl)-1H-pyrazole-4-carbonitrile analogues, employing ammonium acetate as a mild, green catalyst. The proposed methodology provides a rapid, operationally simple, and sustainable approach for the construction of biolo...

M. Kokane, Dnyandev Bhosale, Dattatraya G. Raut et al. · 0 citations

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