Duloxetine for postoperative pain management in total hip and knee arthroplasty: a systematic review and meta-analysis
Postoperative pain following total hip arthroplasty (THA) and total knee arthroplasty (TKA) drives opioid dependence. Perioperative duloxetine is an option as a multimodal analgesic adjunct, yet its efficacy and safety in this population are not fully defined. This systematic review and meta-analysis compared periopera...