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Author

Abdullah Alkhammash

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Open access Sep 2026

Quinazolinone–diarylpyrazole hybrids as dual EGFR/COX-2 inhibitors: antiproliferative, mechanistic, and in silico studies

7f is identified as a promising lead displaying concurrent EGFR and COX-2 inhibitory activity together with pronounced antiproliferative effects, consistent with its experimentally observed dual inhibitory activity.

Abdullah Alkhammash, B. A. Saleem, Khulood H. Oudah et al. · 0 citations
Sep 2026

Targeting TRAF6/MYD88/TLR4, Nrf2, and VEGF signaling pathways by Tranexamic acid as a Novel Therapeutic Approach Protects Against Isotretinoin-Induced Liver Toxicity in Rats.

TXA effectively protects against isotretinoin-induced hepatotoxicity, primarily through antioxidant and anti-inflammatory mechanisms, primarily through antioxidant and anti-inflammatory mechanisms.

Abdullah Alkhammash, H. Hagar, Hatem Ali Ahmed Abdelmottaleb et al. · 0 citations

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