Design of L-borneol-containing biguanide derivatives and their half-sandwich Ru(II)-p-cymene complexes: DNA/HSA binding properties, antioxidant activity and antiproliferative effects in glioblastoma cells.
In this study, half-sandwich Ru(II)-p-cymene complexes containing L-borneol-based biguanide ligands were synthesized, characterized and evaluated for their biological properties. Lipophilicity (logP) and hydrolysis studies demonstrated that the biguanide moiety and its substituents significantly influence hydration beh...