Green Micelle-Enhanced Spectrofluorimetric Determination of Gefitinib in Pharmaceutical Tablets Using Cremophor RH 40: Response-Surface Optimization and Time-Dependent Density Functional Theory (TD-DFT) Interpretation
Gefitinib is an epidermal growth factor receptor inhibitor used in non-small-cell lung cancer. This study developed a micelle-enhanced spectrofluorimetric method for its determination in tablets using native fluorescence and Cremophor RH 40 without derivatization. Experimental conditions were screened by a univariate a...