Author

Abdulrahman S. Alharbi

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Open access Aug 2026

Exploration of thiophene-thiazole and bi-thiophene compounds: Synthesis and molecular modelling as anticancer agents

The current study focused on designing and synthesis of new thiophene-thiazole and bi-thiophene derivatives and evaluate their potential as anticancer agents and carbonic anhydrase inhibitors through experimental and computational investigations. The structure of manufactured thiophene-thiazole and bi-thiophene compo...

Abdulrahman S. Alharbi, Zeyad M. Alharbi, Arwa Alharbi et al. · Arabian Journal of Chemistry · 0 citations

Open access Aug 2026

Synthesis, modelling, biological activity of new thiophene hybridized with pyrazole, and/or pyridine analogues as potential DNA gyrase and topoisomerase IV inhibitors

The study displayed the synthesis of two series of thiophene-pyrazole hybrids, 7a-c and thiophene-pyridine hybrids 9a-c, via reacting arylhydrazone with halogenated reagents and nucleophilic addition of cyanoacetamide to the arylidene-malononitrile, respectively, and the chemical structure was elucidated using relia...

Abdulrahman S. Alharbi, Shadiah Albalawi, Asmaa L Alanzy et al. · Arabian Journal of Chemistry · 0 citations